Gout
Gout
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DOI：
10.1056/nejmcp1001124
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发表时间：
2011-02-03
影响因子：
158.5
通讯作者：
Neogi, Tuhina
中科院分区：
文献类型：
--
作者：
Neogi, Tuhina
一名54岁的男子与水晶证明痛风有四个攻击的历史在过去的一年。尽管每天接受300毫克别嘌呤醇，他的血清尿酸水平为7.2毫克/分升（428 μ mol/L）。他中度肥胖并患有高血压，为此他接受氢氯噻嗪治疗，他的血清肌酐水平为1.0 mg/dl（88 μ mol/L）。他的案子应该如何处理？
A 54-year-old man with crystal-proven gout has a history of four attacks during the previous year. Despite receiving 300 mg of allopurinol daily, his serum urate level is 7.2 mg per deciliter (428 mu mol per liter). He is moderately obese and has hypertension, for which he receives hydrochlorothiazide, and his serum creatinine level is 1.0 mg per deciliter (88 mu mol per liter). How should his case be managed?