Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent
Menorrhagia and reproductive health in rare bleeding disorders: a study from the Indian subcontinent
复制标题
罕见出血性疾病中的月经过多和生殖健康：来自印度次大陆的一项研究
作者：
M. Vijapurkar;L. Mota;S. Shetty;K. Ghosh
抽象的。 在过去 15 年里，该中心对 130 名患有罕见出血性疾病 (RBD) 的女性进行了调查。 50 名患者的初潮年龄超过初潮年龄（印度初潮年龄为 10 岁）。其中 44 人出现月经过多。这些患者的其他并发症包括因格拉夫卵泡破裂而出血 (1)、剖腹产后严重出血 (1)、反复流产 (3)、子宫切除术以控制月经过多 (2)、子宫内膜激光消融 (1) 和卵巢照射 (1)。三名患者自愿选择保持未婚，因为他们认为月经过多会影响婚姻生活。 45名患者全部患有缺铁性贫血。这些患（3）。女性 RBD 诊断较晚，且通常未得到最佳治疗，因此在该国同时遭受医源性和非医源性并发症。
Abstract. At this centre, 130 women with rare bleeding disorders (RBD) were investigated over the past 15 years. Fifty patients were above the age of menarche (age of menarche in India is 10 years). Of these 44 presented with menorrhagia. Other complications in these patients involved bleeding because of ruptured graffian follicle (1), severe haemorrhage following caesarean section (1), recurrent pregnancy losses (3), hysterectomy to control menorrhagia (2), laser ablation of endometrium (1) and irradiation of ovary (1). Three patients voluntarily chose to remain unmarried because of the problems associated with menorrhagia which they assumed will interfere with married life. All the 45 patients had iron deficiency anaemia. The spectrum of RBD in these patients comprised Glanzmann’s thrombasthenia (17), Bernard‐Soulier syndrome (2), storage pool disorder (2), factor V (FV) deficiency (3), combined FV and factor VIII deficiency (5), factor XI deficiency (3), factor XIII deficiency (1), factor X deficiency (5), factor VII deficiency (2), α2‐antiplasmin deficiency (1) and afibrinogenemia (3). RBD in women is diagnosed late and often they are not optimally managed hence suffer both iatrogenic and non‐iatrogenic complications in this country.
由于α2-抗纤溶酶缺乏而导致的出血性疾病。
影响因子：
20.3
作者：
Miles,LA;Plow,EF;Donnelly,KJ;Hougie,C;Griffin,JH
通讯作者：
Griffin,JH