Intraductal Papillary Mucinous Neoplasm of the Pancreas
Intraductal Papillary Mucinous Neoplasm of the Pancreas
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DOI：
10.1016/j.suc.2016.07.009
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发表时间：
2016-12-01
影响因子：
3.1
通讯作者：
Fernandez-del Castillo, Carlos
中科院分区：
文献类型：
--
作者：
Fong, Zhi Ven;Fernandez-del Castillo, Carlos
近二十年来，胰腺导管内乳头状黏液性肿瘤(IPMN)的发病率一直在上升，这主要是由于横断面成像的广泛应用。IPMN是导管内产生粘蛋白的肿瘤，累及主胰管或其侧支，缺乏粘液性囊性肿瘤中常见的卵巢间质。国际胰腺学会在2006年和2012年发布了共识指南，提供了基于IPMN特征和恶性肿瘤风险的临床算法。在这篇文章中，我们回顾了IPMN的不同分类，它们的自然历史和临床治疗，并解决了最近文献中的争议。
The incidence of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas has been rising in the past two decades, driven mainly by the widespread use of cross-sectional imaging. IPMNs are intraductal mucin-producing neoplasms that involve the main pancreatic duct or its side branches and lack the ovarian stroma typically seen in mucinous cystic neoplasms. The International Association of Pancreatology released consensus guidelines in 2006 and 2012 providing clinical algorithms based on IPMN features and risk of malignancy. In this article, we review the different classifications of IPMNs, their natural history, and clinical management and address recent controversies in the literature.