An Electrocatalytic Newman-Kwart-type Rearrangement
An Electrocatalytic Newman-Kwart-type Rearrangement
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DOI：
10.1021/acs.orglett.8b03257
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发表时间：
2018-12-07
期刊：
影响因子：
5.2
通讯作者：
Francke, Robert
中科院分区：
文献类型：
--
作者：
Broese, Timo;Roesel, Arend F.;Francke, Robert
提出了一种O-芳基硫代氨基甲酸酯重排为S-芳基硫代氨基甲酸酯的电化学方法。该协议只需要催化量的电荷，并允许在室温下操作。电解可以用最简单的设备进行，即，在恒电流条件下在未分隔的槽中。此外，它表明，当在微流反应器中进行电解时，几乎可以实现定量产率而不使用支持电解质。
An electrochemical approach toward rearrangement of O-aryl thiocarbamates to the corresponding S-aryl thiocarbamates is presented. The protocol requires only catalytic amounts of electric charge and allows for operation at room temperature. The electrolysis can be carried out with the simplest equipment, i.e., under galvanostatic conditions in an undivided cell. Furthermore, it is demonstrated that when the electrolysis is performed in a microflow reactor, almost quantitative yields can be achieved without using supporting electrolyte.