HYPERTROPHIC SMOOTH-MUSCLE .2. SARCOPLASMIC-RETICULUM, CAVEOLAE AND MITOCHONDRIA

HYPERTROPHIC SMOOTH-MUSCLE .2. SARCOPLASMIC-RETICULUM, CAVEOLAE AND MITOCHONDRIA
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DOI:
10.1007/bf00238049
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发表时间:
1979-01-01
影响因子:
3.6
通讯作者:
GABELLA, G
GABELLA, G
中科院分区:
生物学3区
文献类型:
--
作者:
GABELLA, G

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在实验性狭窄引起肥大的豚鼠小肠中,研究了肥大平滑肌细胞的细胞学特征。通过冷冻断裂,细胞膜似乎比对照肌细胞的膜内颗粒更丰富,而细胞膜的每单位表面的小窝数量显示很少或没有变化(16-19小窝μ m-2)。在肌浆中,光滑和粗糙的肌浆网明显增加;通过表面和体积测量范围。也出现了不寻常的网状结构。线粒体减少(以体积百分比计)至对照值的约一半。
The cytological features of hypertrophic smooth muscle cells are investigated in the small intestine of the guinea pig in which a hypertrophy is induced by an experimental stenosis. By freeze-fracture the cell membrane appears richer in intramembrane particles than that of control muscle cells, whereas the number of caveolae per unit surface of cell membrane shows little or no change (16-19 caveolae .mu.m-2). In the sarcoplasm there is a conspicuous increase of smooth and rough sarcoplasmic reticulum; extent was measured by surface and by volume. Unusual forms of reticulum also appear. Mitochondria are reduced (in percentage volume) to about half the control value.