Global quality of life modifies terminal change in physical functioning among older adult women.

Global quality of life modifies terminal change in physical functioning among older adult women.
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全球生活质量改变了老年女性身体机能的最终变化。

DOI:
10.1093/ageing/afu176
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发表时间:
2015
期刊:
影响因子:
6.7
通讯作者:
Palgi,Yuval
Palgi,Yuval
中科院分区:
医学1区
文献类型:
--
作者:
Shrira,Amit;Zaslavsky,Oleg;LaCroix,AndreaZ;Seguin,Rebecca;Post,Stephen;Tindle,Hilary;Hingle,Melanie;Woods,Nancy;Cochrane,Barbara;Garcia,Lorena;Schnall,Eliezer;Rillamas-Sun,Eileen;Palgi,Yuval

文献摘要

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背景:死亡临近时身体机能适度下降的因素研究不足。本研究的目的是评估死亡相关的全球生活质量(QoL)和身体功能下降,并测试是否基线QoL缓和终端下降在physical functioning.Methods:四千六百五十一名死者从妇女的健康倡议研究(WHI)评定生活质量和身体功能,每年在整个5年follow-up.Results:生活质量和身体功能表现出更陡峭的下降,作为一个功能年死亡比作为一个功能的实足年龄。此外,死者在基线较高的生活质量表现出较低的生活质量在basel.Conclusion:虽然生活质量强烈下降,在终端年,其有益的影响,身体功能是显而易见的,直到生命的最后一天,接近死亡的身体功能。
Background:the factors that moderate decline in physical functioning as death approaches are understudied. This study aimed to assess death-related decline in global quality of life (QoL) and physical functioning and to test whether baseline QoL moderates terminal decline in physical functioning.Methods:four thousand six hundred and fifty-one decedents from the Women's Health Initiative Study (WHI) rated QoL and physical functioning each year throughout 5 years of follow-up.Results:both QoL and physical functioning showed a steeper decline as a function of years to death than as a function of chronological age. Moreover, decedents with higher QoL at baseline showed a less steep decline in physical functioning as death approached than those with lower QoL at baseline.Conclusion:although QoL strongly decreases across the terminal years, its beneficial influence on physical functioning is evident till the very end of life.