A functional magnetic resonance imaging study of the role of left posterior superior temporal gyrus in speech production: implications for the explanation of conduction aphasia
A functional magnetic resonance imaging study of the role of left posterior superior temporal gyrus in speech production: implications for the explanation of conduction aphasia
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DOI：
10.1016/s0304-3940(00)01143-5
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发表时间：
2000-06-23
影响因子：
2.5
通讯作者：
Ugurbil, K
中科院分区：
文献类型：
--
作者：
Hickok, G;Erhard, P;Ugurbil, K
传导性失语以良好的听觉理解和流畅但无序的言语输出为特征，经典地被视为一种脱节综合征。我们回顾了最近的证据，这些证据表明，至少一种形式的传导性失语是由于左侧后颞叶上回皮质区域的损伤所致，该区域不仅参与语音感知，而且参与语音产生的音素方面。作为对这一假设的检验，我们进行了一项4T功能磁共振成像研究，受试者在视觉上以亚声方式呈现物体。基于群体的分析显示，大多数参与者在左侧后颞叶上回的背侧部分显示出两个区域的激活。(C)2000爱思唯尔爱尔兰科学有限公司。保留所有权利。
Conduction aphasia, characterized by good auditory comprehension and fluent but disordered speech production, is classically viewed as a disconnection syndrome. We review recent evidence which suggests that at least one form of conduction aphasia results from damage to cortical fields in the left posterior superior temporal gyrus which participate not only in speech perception, but also in phonemic aspects of speech production. As a test of this hypothesis, we carried out a 4T functional magnetic resonance imaging study in which subjects named visually presented objects sub-vocally. Group-based analyses showed that a majority of participants showed activation in two regions on the dorsal portion of the left posterior superior temporal gyrus. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.