PTSD arousal and depression symptoms associated with increased right-sided parietal EEG asymmetry
PTSD arousal and depression symptoms associated with increased right-sided parietal EEG asymmetry
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DOI：
10.1037/0021-843x.113.2.324
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发表时间：
2004-05-01
影响因子：
4.6
通讯作者：
Orr, SP
中科院分区：
文献类型：
--
作者：
Metzger, LJ;Paige, SR;Orr, SP
研究人员提出，抑郁症和特定类型的焦虑与区域大脑激活的独特模式有关。作者研究了越战女退伍护士的创伤后应激障碍 (PTSD)、焦虑和抑郁症状与额叶、颞叶和顶叶脑电图 α 不对称之间的关系。结果表明，PTSD 唤醒症状与右侧顶叶激活增加有关。然而，与单独的唤醒相比，唤醒、抑郁及其相互作用的结合解释了顶叶不对称性的两倍多。结果支持这样的论点：焦虑与右侧后激活之间的关联是焦虑唤醒亚型所特有的。这些发现强调了在区域大脑激活研究中从理论上和统计学上分离情绪子成分的重要性。
Researchers have proposed that depression and particular types of Anxiety are associated with unique patterns of regional brain activation. The authors examined the relationship among posttraumatic stress disorder (PTSD), anxiety, and depressive symptoms and frontal, temporal, and parietal EEG alpha asymmetry in female Vietnam War nurse veterans. The results indicate that PTSD arousal symptoms are associated with increased right-sided parietal activation. However, the combination of arousal, depression, and their interaction explain more than twice the variance in parietal asymmetry compared with arousal alone. The results support the contention that the association between anxiety and right-sided posterior activation is specific to the anxious arousal subtype. These findings underscore the importance of isolating, both theoretically and statistically, emotional subcomponents in studies of regional brain activation.