A CMOS image sensor with stacked photodiodes for lensless observation system of digital enzyme-linked immunosorbent assay
A CMOS image sensor with stacked photodiodes for lensless observation system of digital enzyme-linked immunosorbent assay
复制标题
用于数字酶联免疫吸附测定无透镜观察系统的堆叠光电二极管 CMOS 图像传感器
DOI:
10.7567/jjap.53.04el02
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发表时间:
2014
影响因子:
1.5
通讯作者:
J. Ohta
中科院分区:
文献类型:
--
作者:
H. Takehara;K. Miyazawa;T. Noda;K. Sasagawa;T. Tokuda;Soo Hyeon Kim;R. Iino;H. Noji;J. Ohta
A CMOS image sensor with stacked photodiodes was fabricated using 0.18 µm mixed signal CMOS process technology. Two photodiodes were stacked at the same position of each pixel of the CMOS image sensor. The stacked photodiodes consist of shallow high-concentration N-type layer (N+), P-type well (PW), deep N-type well (DNW), and P-type substrate (P-sub). PW and P-sub were shorted to ground. By monitoring the voltage of N+ and DNW individually, we can observe two monochromatic colors simultaneously without using any color filters. The CMOS image sensor is suitable for fluorescence imaging, especially contact imaging such as a lensless observation system of digital enzyme-linked immunosorbent assay (ELISA). Since the fluorescence increases with time in digital ELISA, it is possible to observe fluorescence accurately by calculating the difference from the initial relation between the pixel values for both photodiodes.
DOI:
--
发表时间:
2006
期刊:
影响因子:
--
作者:
Yuki Maruyama;Kazuaki Sawada;Hidekuni Takao;Makoto Ishida
通讯作者:
Makoto Ishida
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
中澤寛一;石井広康;石田誠;澤田和明
通讯作者:
澤田和明