Performance of depression rating scales in patients with chronic kidney disease: an item response theory-based analysis.

Performance of depression rating scales in patients with chronic kidney disease: an item response theory-based analysis.
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DOI:
10.1016/j.genhosppsych.2016.07.005
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发表时间:
2016-09
影响因子:
7
通讯作者:
Hedayati SS
Hedayati SS
中科院分区:
医学2区
文献类型:
--
作者:
Toups M;Carmody T;Trivedi MH;Rush AJ;Hedayati SS

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由于抑郁的躯体症状和慢性肾脏疾病(CKD)的症状之间存在重叠,目前尚不清楚自我报告的抑郁评定量表是否可以准确地用于透析前的CKD患者,特别是如果CKD和其他共病是有症状的。我们使用项目反应理论(IRT)对272例透析前CKD患者进行了两种抑郁量表--Beck抑郁量表(BDI)和抑郁症状学快速调查表(QDS-SR16)--在CKD分期、糖尿病诊断和总体医疗共病负担(IRT)方面的评价。我们根据低CKD阶段和高CKD阶段、糖尿病和非糖尿病以及高(3例诊断)和低医疗共病负担来进行IRT。各评定量表的IRT模型受CKD分期、糖尿病和医疗共病负担的影响有限。QDS-SR16上的睡眠障碍对糖尿病患者和有高共病负担的患者的抑郁更具区分性。在高CKD组和高共病组中,来自BDI的悲观和内疚分别比QDS-SR16更能区分抑郁症。总体条目差异不大,慢性病分期、糖尿病或其他内科合并症的严重程度对量表表现的差异没有显著影响。
Because there is overlap between somatic symptoms of depression and symptoms of chronic kidney disease (CKD), it is unclear if self-reported depression rating scales can be used accurately in predialysis CKD patients, especially if CKD and other comorbidities are symptomatic. We assessed the performance of two depression scales — the Beck Depression Inventory (BDI) and the Quick Inventory of Depression Symptomatology (QIDS-SR16) — by CKD stage, diagnosis of diabetes and total medical comorbidity burden —using item response theory (IRT) in a sample of 272 predialysis CKD patients. We performed IRT by low versus high CKD stage, diabetes versus no diabetes and high (>3 diagnoses) versus low medical comorbidity burden. IRT models of each rating scale were affected in a limited way by CKD stage, diabetes and medical comorbidity burden. Sleep disturbances on the QIDS-SR16 were more discriminatory for depression in diabetics and those with high comorbidity burden. Pessimism and guilt from the BDI compared to QIDS-SR16 were more discriminatory of depression in the high CKD and high comorbidity groups, respectively. Overall item differences were modest, and chronic disease severity by CKD stage, diabetes mellitus or other medical comorbidities did not appreciably contribute to differences in scale performance.
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