Difficulties in emotion regulation and impulse control during cocaine abstinence

Difficulties in emotion regulation and impulse control during cocaine abstinence
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DOI:
10.1016/j.drugalcdep.2006.12.026
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发表时间:
2007-07-10
影响因子:
4.2
通讯作者:
Sinha, R.
Sinha, R.
中科院分区:
医学2区
文献类型:
--
作者:
Fox, H. C.;Axelrod, S. R.;Sinha, R.

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基本原理:先前的研究表明,可卡因依赖与涉及情绪和动机状态的脑系统功能障碍有关。目的:使用最近验证的情绪调节困难量表(Difficulties in Emotion Regulation Scale,DERS)来检验情绪调节困难是否与早期可卡因戒断有关。近期寻求戒毒治疗的可卡因患者(n = 60)在住院治疗的第一周和出院时完成了DERS结果:与对照组相比,可卡因依赖者在戒断第1周内出现了与理解情绪、管理情绪和冲动控制有关的困难。随着持续的禁欲,可卡因依赖的个人表现出持续的困难,只有在冲动control.Conclusion:可卡因依赖的个人报告情绪调节困难,特别是在早期禁欲。此外,长期的痛苦相关的冲动控制问题表明潜在的复发脆弱性。(C)2007爱思唯尔爱尔兰有限公司保留所有权利。
Rationale: Prior research has shown that cocaine dependence is associated with dysfunction of brain systems involved in emotions and motivational states.Objectives: To examine whether difficulties in emotion regulation are associated with early cocaine abstinence using the recently validated Difficulties in Emotion Regulation Scale (DERS).Method: Recently abstinent treatment-seeking cocaine patients (n = 60) completed the DERS during their first week of inpatient treatment and at discharge (3-4 weeks later), and scores were compared with community controls (n = 50).Results: Compared with controls, cocaine-dependent individuals reported difficulties relating to understanding emotions, managing emotions and impulse control in the first week of abstinence. With continued abstinence, cocaine-dependent individuals showed continued difficulties only in impulse control.Conclusion: Cocaine-dependent individuals report emotion regulation difficulties, particularly during early abstinence. Additionally, protracted distress-related impulse control problems suggest potential relapse vulnerability. (C) 2007 Elsevier Ireland Ltd. All rights reserved.