Incremental value of biomarkers to clinical variables for mortality prediction in acutely decompensated heart failure: The Multinational Observational Cohort on Acute Heart Failure (MOCA) study
Incremental value of biomarkers to clinical variables for mortality prediction in acutely decompensated heart failure: The Multinational Observational Cohort on Acute Heart Failure (MOCA) study
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DOI：
10.1016/j.ijcard.2013.01.228
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发表时间：
2013-10-03
影响因子：
3.5
通讯作者：
Mebazaa, Alexandre
中科院分区：
文献类型：
--
作者：
Lassus, Johan;Gayat, Etienne;Mebazaa, Alexandre
目的：本研究旨在评估血浆生物标志物对急性失代偿性心力衰竭(ADHF)患者30d和1年死亡率风险分层的传统临床变量的增量价值。方法和结果：通过一个国际协作网络，收集了5306名ADHF住院患者的个体数据。全死因死亡率30天为11.7%，1年为32.9%。临床预测模型(年龄、性别、入院时血压、估计的肾小球滤过率
Aim: This study aims to evaluate the incremental value of plasma biomarkers to traditional clinical variables for risk stratification of 30-day and one-year mortality in acutely decompensated heart failure (ADHF).Methods and results: Through an international collaborative network, individual patient data on 5306 patients hospitalized for ADHF were collected. The all-cause mortality rate was 11.7% at 30 days and 32.9% at one year. The clinical prediction model (age, gender, blood pressure on admission, estimated glomerular filtration rate