Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: a prospective study
Vegetarian diet reduces the risk of hypertension independent of abdominal obesity and inflammation: a prospective study
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DOI：
10.1097/hjh.0000000000001068
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发表时间：
2016-11-01
影响因子：
4.9
通讯作者：
Chiu, Yen-Feng
中科院分区：
文献类型：
--
作者：
Chuang, Shao-Yuan;Chiu, Tina H. T.;Chiu, Yen-Feng
目的：素食可以通过降低肥胖、炎症和胰岛素抵抗的程度来预防血压升高和降低高血压的风险。本研究以台湾非吸烟成人为研究对象，探讨素食饮食与高血压发病率之间的关系，并探讨这种关系是否透过炎症、腹部肥胖或胰岛素抵抗（以空腹血糖为替代指标）介导。方法：这项匹配队列研究来自1994-2008年MJ健康筛查数据库。根据年龄、性别和研究地点，每个素食者与五个非素食者配对。该分析包括4109名不吸烟者（3423名非素食者和686名素食者），随访时间中位数为1.61年。结果包括高血压发病率，以及收缩压和舒张压水平。进行回归分析以评估在潜在介质存在/不存在的情况下，素食与高血压发病率或未来血压水平之间的关系。结果：经年龄和性别调整后，素食者患高血压的风险降低34%(优势比：0.66,95%可信区间：0.50-0.87；收缩压：-3.3mmHg， P
Objectives:A vegetarian diet may prevent elevation of blood pressures and lower the risk for hypertension through lower degrees of obesity, inflammation, and insulin resistance. This study investigated the association between a vegetarian diet and hypertension incidence in a cohort of Taiwanese adult nonsmokers and examined whether this association was mediated through inflammation, abdominal obesity, or insulin resistance (using fasting glucose as a proxy).Methods:This matched cohort study was from the 1994-2008 MJ Health Screening Database. Each vegetarian was matched with five nonvegetarians by age, sex, and study site. The analysis included 4109 nonsmokers (3423 nonvegetarians and 686 vegetarians), followed for a median of 1.61 years. The outcome includes hypertension incidence, as well as SBP and DBP levels. Regression analysis was performed to assess the association between vegetarian diet and hypertension incidence or future blood pressure levels in the presence/absence of potential mediators.Results:Vegetarians had a 34% lower risk for hypertension, adjusting for age and sex (odds ratio: 0.66, 95% confidence interval: 0.50-0.87; SBP: -3.3mmHg, P