New Ligands That Promote Cross-Coupling Reactions between Aryl Halides and Unactivated Arenes
New Ligands That Promote Cross-Coupling Reactions between Aryl Halides and Unactivated Arenes
复制标题
促进芳基卤化物和未活化芳烃之间交叉偶联反应的新配体
DOI：
10.1021/ol2009208
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发表时间：
2011-07-15
期刊：
影响因子：
5.2
通讯作者：
Jiang, Sheng
中科院分区：
文献类型：
--
作者：
Qiu, Yatao;Liu, Yanhan;Jiang, Sheng
设计了几种配体来促进芳基卤与苯衍生物的无过渡金属交叉偶联反应。在所考察的体系中，喹啉-1-氨基-2-羧酸被认为是卤代芳烃与未活化的苯之间交叉偶联的优良催化剂。使用这种廉价的催化体系的反应显示出高的官能团耐受性以及优异的化学选择性。
Several ligands were designed to promote transition-metal-free cross-coupling reactions of aryl halides with benzene derivatives. Among the systems probed, quinoline-1-amino-2-carboxylic acid was found to serve as an excellent catalyst for cross-coupling between aryl halides and unactivated benzene. Reactions using this inexpensive catalytic system displayed a high functional group tolerance as well as excellent chemoselectivities.