Pre-anesthetic presence of an injured dam influences pups' locomotor behavior during emergence from anesthesia in rats.
Pre-anesthetic presence of an injured dam influences pups' locomotor behavior during emergence from anesthesia in rats.
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麻醉前受伤母鼠的存在会影响大鼠麻醉苏醒期间幼崽的运动行为。
DOI：
10.1111/j.1399-6576.2004.00578.x
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Al-Chaer,ED
中科院分区：
文献类型：
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作者：
Arai,Y-CP;Ueda,W;Al-Chaer,ED
背景：麻醉前母婴相互作用是儿科麻醉顺利出现的重要因素。在许多哺乳动物物种中，母婴关系的中断会导致心理和行为的变化。本研究旨在探讨麻醉前是否存在损伤的母鼠对大鼠幼鼠的运动行为有影响。方法：我们使用视频跟踪系统，在40只3周龄的Sprague-道利雄性大鼠中，测试幼鼠和母鼠之间的麻醉前关系对幼鼠从全身麻醉中苏醒时运动行为的影响。幼仔分为两组：与母鼠一起饲养的幼仔（n = 20）和与受伤母鼠一起饲养的幼仔（n = 20）。 用1.2%氟烷麻醉幼仔30分钟。 在出现时，我们记录了他们的运动行为15分钟。结果：对母鼠的预麻醉操作显着增加了幼崽的行走距离。 然而，操作并没有造成任何差异，在最大velocity.Conclusion：麻醉前存在一个受伤的大坝影响幼鼠的运动行为，从麻醉中出现。
Background:Pre‐anesthetic mother–infant interaction is an important factor for smooth emergence of pediatric anesthesia. In many mammalian species, disruptions of the mother–infant relationship cause psychological and behavioral changes. This study was to investigate whether or not pre‐anesthetic presence of an injured dam has an impact on locomotor behavior of rat pups.Methods:We used a video‐tracking system to test the effects of pre‐anesthetic relations between pups and their dams on pups' locomotor behavior during emergence from general anesthesia, in 40 3‐week‐old Sprague‐Dawley male rats. Pups were divided into two groups: pups housed with a dam (n = 20) and those housed with an injured dam (n = 20). Pups were anesthetized with 1.2% halothane for 30 min. At emergence, we recorded their locomotor behavior for 15 min.Results:Pre‐anesthetic manipulation to dams significantly increased the distance traveled by pups. However, the manipulation did not cause any difference in the maximum velocity.Conclusion:Pre‐anesthetic presence of an injured dam influenced pups' locomotor behavior at emergence from anesthesia.