The utility of bone marrow examination in renal transplantation: nine years of experience from north India.
The utility of bone marrow examination in renal transplantation: nine years of experience from north India.
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骨髓检查在肾移植中的效用：印度北部的九年经验。
DOI：
10.1097/01.tp.0000204066.66969.d1
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发表时间：
2006
期刊：
影响因子：
6.2
通讯作者：
V. Sakhuja
中科院分区：
文献类型：
--
作者：
G. Garewal;J. Ahluwalia;Vijay Kumar;R. Shukla;R. Das;N. Varma;V. Sakhuja
肾移植可能会并发持续发烧和血细胞减少。骨髓检查虽然痛苦且具有侵入性，但可能是有价值的，因为大多数外围医院都可以进行，并且可以快速获得结果。在一项回顾性分析中，对 9 年期间 132 名患者的临床记录、骨髓抽吸和环钻活检进行了评估，以确定骨髓检查的指征和结果。在 61 名发烧患者中，有 7 名 (11%) 被确定为特定感染或恶性肿瘤，并且 85% 的病例出现细胞减少。 29% 的病例出现营养缺乏并伴有巨幼细胞增多症或铁储备减少。恶性肿瘤相对较少见（3%）。总体而言，在 12% 的病例中，骨髓检查提供了有用的信息。骨髓检查可能是不明原因发热和血细胞减少的有用诊断测试，特别是在发展中国家。
Renal transplantation may be complicated by persistent fever and cytopenia. Bone marrow examination, though painful and invasive, may be of value because it can be performed in most peripheral hospitals, and the results are rapidly available. In a retrospective analysis, clinical records, marrow aspirates, and trephine biopsies were assessed to determine the indications for bone marrow examination and the findings in 132 patients over a 9-year period. In 7 of 61 (11%) patients with fever, a specific infection or a malignancy was identified, and hypocellularity was seen in 85% of cases. Nutritional deficiency with megaloblastosis or diminished iron stores was noted in 29% of cases. Malignancies were relatively infrequent (3%). Overall, in 12% of the cases, bone marrow examination provided useful information. Examination of the bone marrow may be a useful diagnostic test in pyrexia of unknown origin and cytopenia, particularly in developing countries.