Balsalazide Exposure During the Development of Fertilizing Sperm May Be Associated With Offspring Birth Defects.
Balsalazide Exposure During the Development of Fertilizing Sperm May Be Associated With Offspring Birth Defects.
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受精精子发育过程中接触巴柳氮可能与后代出生缺陷有关。
DOI:
10.1093/ibd/izac038
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发表时间:
2022
影响因子:
4.9
通讯作者:
Eisenberg,MichaelL
中科院分区:
文献类型:
--
作者:
Wensink,MaartenJ;Streett,SarahE;Damkier,Per;Lindahl-Jacobsen,Rune;Kjeldsen,Jens;Eisenberg,MichaelL
Lay SummaryWe report an association between balsalazide exposure during the development of fertilizing sperm and birth defects in offspring. Exposed offspring were approximately 8 times more likely to have a birth defect. There were no pre-existing reasons to suspect such a relationship, which should be confirmed in other data.