FABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue‐derived hormone levels in mouse models mimicking constipation‐predominant IBS
FABP4 blocker attenuates colonic hypomotility and modulates white adipose tissue‐derived hormone levels in mouse models mimicking constipation‐predominant IBS
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DOI：
10.1111/nmo.13272
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发表时间：
2018-05
影响因子：
3.5
通讯作者：
P. Mosińska;D. Jacenik;M. Sałaga;A. Wasilewski;A. Cygankiewicz;A. Sibaev;A. Mokrowiecka;Ewa Małecka-Panas;I. Pintelon;Martin Storr;Jean-Pierre Timmermans;Wanda M. Krajewska;J. Fichna
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文献类型：
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作者：
P. Mosińska;D. Jacenik;M. Sałaga;A. Wasilewski;A. Cygankiewicz;A. Sibaev;A. Mokrowiecka;Ewa Małecka-Panas;I. Pintelon;Martin Storr;Jean-Pierre Timmermans;Wanda M. Krajewska;J. Fichna
脂肪酸结合蛋白4（FABP4）在下消化道（GI）运动中的作用尚不清楚。我们的目的是验证体内抑制FABP4对GI转运的影响，并确定FABP4在小鼠和人组织中的表达。
The role of fatty acid binding protein 4 (FABP4) in lower gastrointestinal (GI) motility is unknown. We aimed to verify the effect of inhibition of FABP4 on GI transit in vivo, and to determine the expression of FABP4 in mouse and human tissues.