Relationships between blood pressure and blood glucose among offspring of parents with type 2 diabetes: Prediction of incident dysglycemia in a biracial cohort
Relationships between blood pressure and blood glucose among offspring of parents with type 2 diabetes: Prediction of incident dysglycemia in a biracial cohort
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DOI：
10.1016/j.jdiacomp.2017.07.019
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发表时间：
2017-11-01
影响因子：
3
通讯作者：
Dagogo-Jack, Sam
中科院分区：
文献类型：
--
作者：
Edeoga, Chimaroke;Owei, Ibiye;Dagogo-Jack, Sam
目的：我们评估了健康受试者的血压(BP)和血糖(BG)值，并在随访期间检测基线血压作为糖尿病前期发病的预测因子。方法：在一项双相队列(POP-ABC)研究中，糖尿病前期病理生物学的参与者接受了筛查评估(人体测量、血压、OGTT)，并将其分为正常血压(NBP)、高血压前期或高血压、正常血糖调节(NGR)、糖尿病前期(IFG/IGT)或2型糖尿病(T2D)状态。结果：我们筛查了602名成年人(黑人341人，白人261人)，并招募了343人(黑人193人，白人150人)进行前瞻性随访，发现收缩压和舒张压与空腹和非空腹血糖显著相关(P=0.003)。
Aims: We assessed blood pressure (BP) and blood glucose (BG) values in healthy subjects, and examined baseline BP as a predictor of incident prediabetes during follow-up.Methods: Participants in the Pathobiology of Prediabetes in a Biracial Cohort (POP-ABC) study underwent screening assessments (anthropometry, BP, OGTT) and were stratified into normal BP (NBP), prehypertension, or hypertension, and normal glucose regulation (NGR), prediabetes (IFG/IGT), or type 2 diabetes (T2D) status. NGR subjects who met all inclusion criteria were enrolled in a 5-yr prospective study, with the primary outcome of incident prediabetes.Results: We screened 602 adults (341 black, 261 white) and enrolled 343 (193 black, 150 white) for prospective follow-up, Systolic and diastolic BP correlated significantly with fasting and nonfasting BG (P = 0.003-