Oncogenic Human Papillomavirus Infections in 18- to 24-Year-Old Female Online Daters.
Oncogenic Human Papillomavirus Infections in 18- to 24-Year-Old Female Online Daters.
复制标题
18 至 24 岁女性在线约会者的致癌人乳头瘤病毒感染。
DOI：
10.1097/olq.0000000000000331
复制
发表时间：
2015
影响因子：
3.1
通讯作者：
Winer,RachelL
中科院分区：
文献类型：
--
作者：
Barrere,Alexis;Stern,JoshuaE;Feng,Qinghua;Hughes,JamesP;Winer,RachelL
BackgroundAlthough年轻女性HPV感染的危险因素是明确的，与会议男性性伴侣通过Internet.MethodsWe分析了282名妇女年龄在18至24岁的横断面数据，报告使用互联网约会网站在过去的一年中，通过互联网的风险是不清楚的。妇女邮寄阴道自我采样工具包聚合酶链反应为基础的HPV基因分型（包括19个致癌类型）和性行为和健康史问卷。广义线性模型被用来评估流行致癌HPV infection.Results35%的妇女报告说，在过去的6个月里，通过互联网遇到了一个男性性伴侣，42%的HPV疫苗接种的历史。致癌HPV感染的患病率为37%，9%的女性HPV-16或HPV-18检测呈阳性。在过去6个月内通过互联网认识男性性伴侣与致癌HPV感染没有显著相关性。在多变量分析中，与致癌性HPV感染可能性增加相关的变量包括过去6个月内报告至少有1个并发伴侣的男性伴侣（调整后的患病率[aPR]，1.51; 95%置信区间[CI]，1.11-2.06），在过去6个月内与男性伴侣不总是使用避孕套（aPR，1.86; 95% CI，1.05-3.30）。自我报告接受至少1剂HPV疫苗的历史与HPV-16或HPV-18检测阳性呈负相关（aPR，0.39; 95%CI，0.16-0.97）。
BackgroundAlthough risk factors for HPV infections in young women are well defined, the risk associated with meeting male sex partners via the Internet is unclear.MethodsWe analyzed cross-sectional data from 282 women aged 18 to 24 years who reported using Internet dating Web sites in the past year. Women were mailed vaginal self-sampling kits for polymerase chain reaction–based HPV genotyping (including 19 oncogenic types) and sexual behavior and health history questionnaires. Generalized linear models were used to evaluate risk factors for prevalent oncogenic HPV infections.ResultsThirty-five percent of women reported having met a male sex partner via the Internet in the past 6 months, and 42% reported a history of HPV vaccination. The prevalence of oncogenic HPV infection was 37%, and 9% of women tested positive for HPV-16 or HPV-18. Having met a male sex partner via the Internet in the past 6 months was not significantly associated with oncogenic HPV infection. In multivariate analyses, variables associated with an increased likelihood of oncogenic HPV infection included male partners in the past 6 months who were reported to have at least 1 concurrent partnership (adjusted prevalence ratio [aPR], 1.51; 95% confidence interval [CI], 1.11–2.06) and not always using condoms with male partners in the past 6 months (aPR, 1.86; 95% CI, 1.05–3.30). Self-reporting a history of receiving at least 1 dose of HPV vaccine was inversely associated with testing positive for HPV-16 or HPV-18 (aPR, 0.39; 95% CI, 0.16–0.97).ConclusionsAlthough measures of recent sexual behavior were associated with prevalent oncogenic HPV infection, male partners met online were not associated with an increased likelihood of infection in this cohort of young women.