Cancer mortality trend analysis in Italy, 1970-2007
Cancer mortality trend analysis in Italy, 1970-2007
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DOI：
10.1097/cej.0b013e328345f99e
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发表时间：
2011-09-01
影响因子：
2.4
通讯作者：
Negri, Eva
中科院分区：
文献类型：
--
作者：
Arfe, Andrea;Malvezzi, Matteo;Negri, Eva
为了提供意大利癌症死亡率趋势的最新回顾，从WHO死亡率数据库中提取了1970年至2007年的癌症死亡率和人口普查数据，并使用年龄特异性和标准化率以及联合点回归进行了分析。自1994年以来，男性癌症总死亡率每年下降1.8%，2007年达到每10万居民147人（世界标准）。在妇女中，自1991年以来，癌症总死亡率每年下降1.1%，2007年的标准化死亡率为每10万居民85人。与1988年相比，避免死于肺癌、肠癌、胃癌和乳腺癌的人数为30 646人。在男性中，趋势是由肺癌和其他与烟草相关的部位，肠道和胃的癌症驱动的。乳腺癌、肠癌、胃癌和子宫癌的有利趋势有助于妇女死亡率的福尔斯下降。两性的霍奇金淋巴瘤、骨癌和白血病的发病率均呈下降趋势。女性肺癌呈上升趋势，死亡率自1997年以来每年上升2.6%，成为中年女性癌症死亡的第二位原因。女性口腔癌和胰腺癌的发病率也呈上升趋势。癌症死亡率的有利趋势与男性吸烟和饮酒的减少，结肠直肠癌，乳腺癌，白血病和其他一些罕见的可治疗癌症的治疗和管理的进步以及结肠直肠癌，乳腺癌和宫颈癌的诊断改善有关。与烟草有关的死亡在妇女中所起的作用更大，这表明需要有针对性的战略。欧洲癌症预防杂志20：364-374（C）2011年沃尔特斯·克鲁沃健康垂直酒吧利平科特威廉姆斯&威尔金斯。
To provide an updated review of cancer mortality trends in Italy, cancer mortality and census data, from 1970 to 2007, were extracted from the WHO mortality database and analyzed using age-specific and standardized rates, and joinpoint regression. Total cancer mortality rates in men have been declining by 1.8% yearly since 1994, reaching a rate of 147 per 100 000 residents (world standard) in 2007. In women, total cancer mortality rates have been decreasing by 1.1% yearly since 1991, resulting in a standardized mortality rate of 85 per 100 000 residents in 2007. Avoided deaths, compared with rates of 1988, from lung, intestinal, stomach, and breast cancers amount to 30 646. In men, trends were driven by cancers of the lung and other tobacco-related sites, intestines, and stomach. Favorable trends for cancers of the breast, intestines, stomach, and uterus contributed to falls in mortality rate in women. Downward trends were seen in both sexes for Hodgkin's lymphoma, bone cancer, and leukemias. Lung cancer in women showed an upward trend, with mortality rates increasing by 2.6% yearly since 1997, becoming the second cause of cancer mortality in middle-aged women. Rising trends were seen in women for oral and pancreatic cancers, as well. The favorable trends in cancer mortality are related to reduced tobacco smoking and alcohol consumption in men, advancements in treatment and management for colorectal cancer, breast cancer, leukemias, and a few other rare treatable cancers, and improved diagnosis of colorectal, breast, and cervical cancers. The greater role of tobacco-related deaths in women suggests the need for targeted strategies. European Journal of Cancer Prevention 20: 364-374 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.