THE POPULATION GENETICS OF PHENOTYPIC DETERIORATION IN EXPERIMENTAL POPULATIONS OF BACILLUS SUBTILIS
THE POPULATION GENETICS OF PHENOTYPIC DETERIORATION IN EXPERIMENTAL POPULATIONS OF BACILLUS SUBTILIS
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DOI：
10.1111/j.0014-3820.2006.tb01148.x
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发表时间：
2006-04
期刊：
影响因子：
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通讯作者：
H. Maughan;Victoria Callicotte;Adam Hancock;C. Birky;W. Nicholson;J. Masel
中科院分区：
文献类型：
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作者：
H. Maughan;Victoria Callicotte;Adam Hancock;C. Birky;W. Nicholson;J. Masel
摘要虽然自然界中存在许多性状丢失的例子，但导致这种丢失的潜在群体遗传机制通常是未知的。选择性或中性的过程可能会导致性状的恶化，而其中之一往往是基于间接证据而推断出来的。此外，特定环境特有的选择压力以及这些压力可能对导致性状丧失的群体遗传原因的影响还没有被很好地理解。在这里，我们描述了一个实验进化系统，其中使用了两个不同的环境来解决整个进化过程中导致性状丧失的群体遗传原因。我们发现，无论实验环境如何，所有种群在最低限度(即原生营养)中的生长都会丢失，其中一个环境中的性状丢失模式是由于选择造成的，而在另一个环境中，原因尚不确定。
Abstract Although many examples of trait loss exist in nature, the underlying population genetic mechanism responsible for the loss is usually unknown. Selective or neutral processes can result in the deterioration of a trait, and often one of these is inferred based on indirect evidence. Furthermore, selective pressures that are unique to particular environments and the effect these might have on the population genetic cause of trait loss are not well understood. Here we describe an experimental evolution system where two different environments were used for addressing the population genetic cause of trait loss throughout evolutionary time. We found that growth in minimal medium (i.e., prototrophy) was lost in all populations regardless of the experimental environment and that the pattern of trait loss in one environment was due to selection, whereas in the other environment the cause remains inconclusive.