Turmeric and Green Tea: A Recipe for the Treatment of B-Chronic Lymphocytic Leukemia

Turmeric and Green Tea: A Recipe for the Treatment of B-Chronic Lymphocytic Leukemia
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DOI:
10.1158/1078-0432.ccr-08-2791
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发表时间:
2009-02-15
影响因子:
11.5
通讯作者:
Kurzrock, Razelle
Kurzrock, Razelle
中科院分区:
医学1区
文献类型:
--
作者:
Angelo, Laura S.;Kurzrock, Razelle

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两种自然存在的化合物,香料姜黄中的活性成分姜黄素和绿茶提取物表没食子儿茶素没食子酸酯,对慢性淋巴细胞白血病的凋亡机制有显著的影响。这些结果为未来这些化合物在该疾病中的临床应用提供了临床前基础。
Two naturally occurring compounds, curcumin, the active ingredient in the spice turmeric, and the green tea extract epigallocatechin-3-gallate, have marked effects on the apoptotic machinery in chronic lymphocytic leukemia. These results provide a preclinical foundation for future clinical use of these compounds in this disease.