Sleep symptomatology is associated with greater subjective cognitive concerns: findings from the community-based Healthy Brain Project.
Sleep symptomatology is associated with greater subjective cognitive concerns: findings from the community-based Healthy Brain Project.
复制标题
睡眠症状与更大的主观认知问题相关：基于社区的健康大脑项目的发现。
DOI：
10.1093/sleep/zsab097
复制
发表时间：
2021
期刊：
影响因子：
5.6
通讯作者：
Pase,MatthewP
中科院分区：
文献类型：
--
作者：
Nicolazzo,Jessica;Xu,Katharine;Lavale,Alexandra;Buckley,Rachel;Yassi,Nawaf;Hamilton,GarunS;Maruff,Paul;Baril,Andree-Ann;Lim,YenYing;Pase,MatthewP
研究目的在无痴呆症的社区样本中，检验睡眠症状是否与主观认知担忧或客观认知表现有关。方法来自健康大脑计划的1,421名中年参与者(平均±标准差=57±7；77%女性)分别完成匹兹堡睡眠质量指数、失眠严重程度指数和Epworth嗜睡量表，以测量睡眠质量、失眠症状严重程度和日间困倦。使用设定的分界值，参与者被分为没有睡眠症状(每项睡眠指标的得分正常)、中度睡眠症状(一项睡眠指标的得分异常)或高睡眠症状(至少两项睡眠指标的异常得分)。结果在调整了年龄、性别、教育程度、情绪和血管危险因素后，高睡眠症状者与无高睡眠症状者相比，表现出更多的主观认知担忧(d=0.24)，但客观认知表现没有差异(d=0.00~0.18)。主观认知方面的担忧改变了睡眠症状和精神运动功能之间的联系。高睡眠症状者(与无高睡眠症状者相比)与精神运动功能的相关性显著高于低认知忧虑者(β±SE=−0.37±0.16；p=0.0 2)。结论睡眠症状越重，主观认知忧虑性越强。报告睡眠症状水平高的人可能更有可能在存在主观认知担忧的情况下表现出较差的客观认知功能。
Study ObjectivesTo examine if sleep symptomatology was associated with subjective cognitive concerns or objective cognitive performance in a dementia-free community-based sample.MethodsA total of 1,421 middle-aged participants (mean ± standard deviation = 57 ± 7; 77% female) from the Healthy Brain Project completed the Pittsburgh Sleep Quality Index, Insomnia Severity Index, and Epworth Sleepiness Scale to measure sleep quality, insomnia symptom severity, and daytime sleepiness, respectively. Participants were classified as having no sleep symptomatology (normal scores on each sleep measure), moderate sleep symptomatology (abnormal scores on one sleep measure), or high sleep symptomatology (abnormal scores on at least two sleep measures), using established cutoff values. Analysis of covariance was used to compare objective cognitive function (Cogstate Brief Battery) and subjective cognitive concerns (Modified Cognitive Function Instrument) across groups.ResultsFollowing adjustments for age, sex, education, mood, and vascular risk factors, persons classified as having high sleep symptomatology, versus none, displayed more subjective cognitive concerns (d= 0.24) but no differences in objective cognitive performance (d= 0.00–0.18). Subjective cognitive concerns modified the association between sleep symptomatology and psychomotor function. The strength of the relationship between high sleep symptomatology (versus none) and psychomotor function was significantly greater in persons with high as compared with low cognitive concerns (β±SE= −0.37 ± 0.16;p= 0.02).ConclusionsMore severe sleep symptomatology was associated with greater subjective cognitive concerns. Persons reporting high levels of sleep symptomatology may be more likely to display poorer objective cognitive function in the presence of subjective cognitive concerns.