Prevalence of suboptimal vitamin D status during pregnancy.
Prevalence of suboptimal vitamin D status during pregnancy.
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怀孕期间维生素 D 状态欠佳的普遍情况。
作者：
M. O'Riordan;M. Kiely;J. Higgins;K. Cashman
母亲维生素 D 水平较低与宫内长骨生长减少、妊娠期缩短、出生体重下降以及儿童期骨矿物质积累减少有关。尽管其他国家的数据表明孕期孕妇维生素 D 水平较低的情况很常见，但爱尔兰女性群体怀孕期间缺乏维生素 D 水平的信息。因此，我们前瞻性评估了一组爱尔兰孕妇的维生素 D 营养状况和维生素 D 状况欠佳的患病率。孕妇组的维生素 D 每日平均摄入量 (SD) 为 3.6 (1.9) 微克/天。所有女性均未达到爱尔兰孕妇建议的每日维生素 D 摄入量（10 微克/天）。就所有三个妊娠期而言，14.3-23.7% 和 34.3-52.6% 的爱尔兰女性在怀孕期间分别存在维生素 D 缺乏（血清 25 (OH) D <25 nmol/l）和不足（血清 25 (OH) D 25-50 nmol/l）。血清 25 (OH)D 水平和维生素 D 缺乏/充足的患病率均受到季节的显着影响，在延长的冬季期间状况最低，在延长的夏季期间状况最好。这些研究结果表明，维生素 D 不足在爱尔兰孕妇中很常见。
Low maternal vitamin D status has been associated with reduced intrauterine long bone growth and shorter gestation, decreased birth weight, as well as reduced childhood bone-mineral accrual. Despite data from other countries indicating low maternal vitamin D status is common during pregnancy, there is a dearth of information about vitamin D status during pregnancy in the Irish female population. Therefore, we prospectively assessed vitamin D nutritive status and the prevalence of suboptimal vitamin D status in a cohort of Irish pregnant women. The mean (SD) daily intake of vitamin D by the group of pregnant women was 3.6 (1.9) microg/day. None of the women achieved the recommended daily vitamin D intake value for Irish pregnant women (10 microg/day). Taking all three trimesters collectively, 14.3-23.7% and 34.3-52.6% of Irish women had vitamin D deficiency (serum 25 (OH) D <25 nmol/l) and insufficiency (serum 25 (OH) D 25-50 nmol/l), respectively during pregnancy. Both the levels of serum 25 (OH) D and the prevalence of vitamin D deficiency/adequacy were dramatically influenced by season, with status being lowest during the extended winter period and best during the extended summer period. These findings show that inadequate vitamin D status is common in Irish pregnant women.