Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.
Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.
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DOI：
10.1111/jmp.12177
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发表时间：
2015-10
影响因子：
0.7
通讯作者：
Kersh EN
中科院分区：
文献类型：
--
作者：
Morris MR;Byrareddy SN;Villinger F;Henning TC;Butler K;Ansari AA;McNicholl JM;Kersh EN
月经周期期间不同的易感性可能是雌性恒河猴感染 S(H)IV 风险的一个因素。我们回顾性地确定了一组参与 HIV 传播试验的恒河猴 (n = 11) 相对于月经周期的阴道 SIV 感染时间点。九只恒河猴中有八只在月经期间被感染。
Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques. We retrospectively determined vaginal SIV infection time points relative to the menstrual cycle in a group of rhesus macaques (n = 11) enrolled in an HIV transmission trial. Eight of nine rhesus macaques became infected around menstruation time.