Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California
Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California
复制标题
DOI：
10.1136/jech.2009.083576
复制
发表时间：
2010-02-01
影响因子：
6.3
通讯作者：
Ritz, Beate
中科院分区：
文献类型：
--
作者：
Meng, Ying-Ying;Rull, Rudolph P.;Ritz, Beate
背景加州的圣华金河谷（SJV）是美国空气质量最差的地区之一，其居民报告的哮喘症状和哮喘相关急诊（艾德）就诊率和住院率在加州中最高。使用加州健康访谈调查数据，作者研究了空气污染和哮喘发病率之间的关联，在这个region.Methods符合条件的受试者是SJV居民（2001年加州健康访谈调查）谁报告医生诊断的哮喘（n = 1502，14.6%）。作者认为有两种结果表明哮喘未得到控制：（1）每日或每周哮喘症状和（2）过去一年中哮喘相关艾德访视或住院。根据居民区的邮政编码，对受试者分配臭氧、PM（10）和PM的年平均浓度（2.5）在访谈日期之前的1年内，从他们最近的政府空气监测站在8公里（5英里）半径内。结果调整年龄，性别，种族/民族，贫困水平和保险状况，作者观察到，每天或每周出现哮喘症状的几率增加，（2.5）（OR（臭氧）1.23，95% CI 0.94 - 1.60/10 ppb; OR（PM10）1.29，95% CI 1.05 - 1.57/10 μ g/m（3）; OR（PM2.5）1.82; 95% CI 1.11 - 2.98/10 μ g/m（3））。作者还观察到与哮喘相关的艾德就诊或因臭氧而住院的几率增加（OR 1.49，95% CI 1.05至2.11/10 ppb），PM的几率增加29%（10）（OR 1.29，95% CI 0.99 - 1.69/10 μ g/m（3））。这些发现表明，生活在具有高臭氧和颗粒污染水平的SJV区域的哮喘患者更可能具有频繁的哮喘症状和与哮喘相关的艾德就诊和住院。
Background The San Joaquin Valley (SJV) in California ranks among the worst in the USA in terms of air quality, and its residents report some of the highest rates of asthma symptoms and asthma-related emergency department (ED) visits and hospitalisations in California. Using California Health Interview Survey data, the authors examined associations between air pollution and asthma morbidity in this region.Methods Eligible subjects were SJV residents (2001 California Health Interview Survey) who reported physician-diagnosed asthma (n = 1502, 14.6%). The authors considered two outcomes indicative of uncontrolled asthma: (1) daily or weekly asthma symptoms and (2) asthma-related ED visits or hospitalisation in the past year. Based on residential zip code, subjects were assigned annual average concentrations of ozone, PM(10) and PM(2.5) for the 1-year period prior to the interview date from their closest government air monitoring station within an 8 km (5 miles) radius.Results Adjusting for age, gender, race/ethnicity, poverty level and insurance status, the authors observed increased odds of experiencing daily or weekly asthma symptoms for ozone, PM(10) and PM(2.5) (OR(ozone) 1.23, 95% CI 0.94 to 1.60 per 10 ppb; OR(PM10) 1.29, 95% CI 1.05 to 1.57 per 10 mu g/m(3); and OR(PM2.5) 1.82; 95% CI 1.11 to 2.98 per 10 mu g/m(3)). The authors also observed increased odds of asthma-related ED visits or hospitalisations for ozone (OR 1.49, 95% CI 1.05 to 2.11 per 10 ppb) and a 29% increase in odds for PM(10) (OR 1.29, 95% CI 0.99 to 1.69 per 10 mu g/m(3)).Conclusions Overall, these findings suggest that individuals with asthma living in areas of the SJV with high ozone and particulate pollution levels are more likely to have frequent asthma symptoms and asthma-related ED visits and hospitalisations.