Germination and Resistance Defects in Spores of a Bacillus subtils Mutant Lacking a Coat Polypeptide
Germination and Resistance Defects in Spores of a Bacillus subtils Mutant Lacking a Coat Polypeptide
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缺乏衣壳多肽的枯草芽孢杆菌突变体孢子的萌发和抗性缺陷
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发表时间：
1981
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通讯作者：
H. Jenkinson
中科院分区：
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作者：
H. Jenkinson
枯草杆菌突变体产生的孢子萌发缓慢，对溶菌酶敏感。突变体的孢子外壳似乎缺乏单一多肽（mol. wt 36000），其通常在孢子形成的阶段V期间沉积在孢子的外层中。B上leuA和argA之间的突变图。在枯草杆菌染色体上，并且在基因型和表型上不同于定位在相同区域中的另一个突变格尔-36：因此，它已被指定为新的基因座spoVIA。突变体的表型证实了先前的建议，即溶菌酶抗性是由孢子外壳的最外层赋予的。
Spores produced by a mutant of Bacillus subtilis germinate slowly and are sensitive to lysozyme. The spore coat of the mutant appears to lack a single polypeptide (mol. wt 36000) which normally is deposited in the outer layers of the spore during stage V of sporulation. The mutation maps between leuA and argA on the B. subtilis chromosome and is genotypically and phenotypically distinct from another mutation ger-36 which maps in the same region: consequently it has been assigned a new locus spoVIA. The phenotype of the mutant confirms a previous suggestion that lysozyme resistance is conferred by the outermost layers of the spore coat.