RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSE
RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSE
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DOI：
10.1172/jci103259
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发表时间：
1956-01-01
影响因子：
15.9
通讯作者：
DOLE, VP
中科院分区：
文献类型：
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作者：
DOLE, VP
血浆中非酯化脂肪酸（NEFA）浓度随禁食而升高，在混合餐、口服葡萄糖（50 g）或注射胰岛素（0.1 [mu]/kg）后降低，在注射肾上腺素（0.5 mg）后显著升高。另一方面，即使摄入足够的玉米油产生严重的脂血症，也不能引起任何变化。3例血浆总脂、中性脂肪、胆固醇和磷脂慢性升高者，空腹NEFA水平正常。本文介绍了一种测定NEFA的新方法。它似乎比以前的技术更快速和灵敏。
The concentration of non-esterified fatty acids (NEFA) in plasma increased with fasting, decreased after a mixed meal, oral glucose (50 g) or injected insulin (0.1 [mu]/kg), and rose markedly alter injection of epinephrine (0.5 mg). Corn oil, on the other hand, failed to cause any change even when enough was taken to produce gross lipemia. The fasting levels of NEFA were normal in 3 men with chronic elevation of total plasma lipids, neutral fat, cholesterol and phospholipids. A new method for determination of NEFA is described. It appears to be more rapid and sensitive than previous techniques.