HEMIBALLISM-HEMICHOREA - CLINICAL AND PHARMACOLOGIC FINDINGS IN 21 PATIENTS
HEMIBALLISM-HEMICHOREA - CLINICAL AND PHARMACOLOGIC FINDINGS IN 21 PATIENTS
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DOI：
10.1001/archneur.1989.00520440044020
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发表时间：
1989-08-01
影响因子：
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通讯作者：
JANKOVIC, J
中科院分区：
文献类型：
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作者：
DEWEY, RB;JANKOVIC, J
在这一系列的21例偏侧舞蹈症患者中，我们发现了一个可识别的原因。不像大多数其他研究中，中风是运动障碍的最重要的原因，在我们的患者中，几乎一半（10/21）的其他原因被发现。偏侧舞蹈症，偏侧舞蹈症往往是潜在的医疗疾病的表现特征。除了丘脑底核，其他皮质下结构可能参与这种偏侧运动过度的发病机制。虽然运动障碍通常会自发改善或通过药物治疗改善，但基础疾病可能会导致严重后果。
In this series of 21 patients with hemiballism-hemichorea we found an identifiable cause in all. Unlike most other studies in which stroke was the most important cause of the movement disorder, in almost half (10 of 21) of our patients some other cause was found. Hemiballism-hemichorea was often the presenting feature of underlying medical disease. Besides the subthalamic nucleus, other subcortical structures may be involved in the pathogenesis of this hemihyperkinesia. While the movement disorder often improves spontaneously or with pharmacologic therapy, the underlying disease may result in serious consequences.