Divergent strategy in natural product total synthesis
Divergent strategy in natural product total synthesis
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DOI：
10.1016/j.tetlet.2014.09.078
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发表时间：
2014-11-05
影响因子：
1.8
通讯作者：
Shimokawa, Jun
中科院分区：
文献类型：
--
作者：
Shimokawa, Jun
天然产物合成中的发散策略可以实现家族天然产物的综合合成。这一想法的有效制定需要生物合成/生物合成启发的洞察力，对多能后期中间体的精心设计，伴随着中间体的适用性，用于多功能转化。本文摘着重于这些策略在天然产物合成中的实际应用，重点是选择常见中间体的配方。(C)2014作者爱思唯尔有限公司出版
Divergent strategy in natural product synthesis allows the comprehensive synthesis of family natural products. Efficient formulation of this idea requires the biosynthetic/biosynthesis-inspired insight toward the well-orchestrated design of a pluripotent late-stage intermediate, in concomitant with the applicability of the intermediates for versatile transformations. This digest focuses on the actual applications of those strategies in natural product synthesis with an emphasis on the recipes for the choice of the common intermediates. (C) 2014 The Author. Published by Elsevier Ltd.