Quantitative 19F imaging using inductively coupled reference signal injection.
Quantitative 19F imaging using inductively coupled reference signal injection.
复制标题
使用电感耦合参考信号注入进行定量 19F 成像。
DOI：
10.1002/mrm.22298
复制
发表时间：
2010
影响因子：
3.3
通讯作者：
Mathis,Mark
中科院分区：
文献类型：
--
作者：
Lee,Donghoon;Marro,Kenneth;Shankland,Eric;Mathis,Mark
本报告介绍了我们最近的努力，我们不断发展的合成信号注入方法的定量代谢物含量的MR波谱和MRI。以前的工作表明，光谱峰的代谢物含量的定量单位的转换可以实现与校准的合成自由感应衰减产生的电感耦合注射线圈。这项工作表明，校准的合成体素，以相同的方式注入，可以用来量化代谢物的含量在real 19 F图像体素。通过参考预先校准的合成注射的体素，将含有不同浓度的氟化钠（NaF）的小瓶的图像转换为摩尔单位。含有不同氯化钠（NaCl）的小瓶的其他图像证明，定量过程具有稳健性，且不受弹簧圈装载条件变化的影响。Magn Reson Med 63：570-573，2010.© 2010 Wiley利斯公司
This report describes recent efforts on our continuous development of a synthetic signal injection method for quantification of metabolite content in MR spectroscopy and MRI. Previous work showed that conversion of spectral peaks to quantitative units of metabolite content could be achieved with a calibrated synthetic free induction decay generated by an inductively coupled injection coil. This work demonstrates that calibrated synthetic voxels, injected in the same manner, can be used to quantify metabolite content in real19F image voxels. Images of vials containing different concentrations of sodium fluoride (NaF) were converted to units of moles by reference to precalibrated synthetically injected voxels. Additional images of vials containing variable sodium chloride (NaCl) demonstrate that the quantification process is robust and immune to changes in coil loading conditions. Magn Reson Med 63:570–573, 2010. © 2010 Wiley‐Liss, Inc.