Formal thought disorder and psychopathology in pediatric primary generalized and complex partial epilepsy
Formal thought disorder and psychopathology in pediatric primary generalized and complex partial epilepsy
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DOI：
10.1097/00004583-199709000-00022
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发表时间：
1997-09-01
影响因子：
13.3
通讯作者：
Chayasirisobhon, S
中科院分区：
文献类型：
--
作者：
Caplan, R;Arbelle, S;Chayasirisobhon, S
目的：探讨复杂部分性癫痫（CPS）患儿是否存在形式思维障碍和精神病理，而非原发性全身性癫痫伴缺席（PGE）患儿或非癫痫患儿。方法：对30例CPS患儿、24例PGE患儿和61例非癫痫患儿进行形式思维障碍编码，并对癫痫患者进行结构化访谈精神科诊断。结果：CPS组的非逻辑思维明显多于PGE组和非癫痫组。他们的逻辑思维严重程度与整体认知功能障碍和精神分裂症样精神病有关。然而，在PGE组中，发病年龄和癫痫控制与非逻辑思维的严重程度显著相关。在63%的CPS患者和54%的PGE患者中发现了一种或多种精神病学诊断，特别是如果他们有整体认知缺陷。结论：与认知功能障碍或精神分裂症样症状相关的非逻辑思维可能是儿童CPS的一个特征。精神病理可能与儿童CPS和PGE的整体认知功能障碍有关。
Objective: To examine whether formal thought disorder and psychopathology occurred in children with complex partial seizures (CPS) rather than children with primary generalized epilepsy with absences (PGE) or nonepileptic children. Method: Formal thought disorder was coded in 30 children with CPS, 24 children with PGE, and 61 nonepileptic children, and structured interview-based psychiatric diagnoses were obtained for the epileptic subjects. Results: The CPS subjects had significantly more illogical thinking than the PGE and nonepileptic children. The severity of their illogical thinking was related to global cognitive dysfunction and a schizophrenia-like psychosis. Age of onset and seizure control, however, were significantly associated with the severity of illogical thinking in the PGE group. One or more psychiatric diagnoses were found in 63% of the CPS and 54% of the PGE patients, particularly if they had global cognitive deficits. Conclusion: Illogical thinking, associated with cognitive dysfunction or schizophrenia-like symptoms, might be a feature of pediatric CPS. Psychopathology might be related to global cognitive dysfunction in pediatric CPS and PGE.