Health-related quality of life of women with menopausal hot flushes and night sweats
Health-related quality of life of women with menopausal hot flushes and night sweats
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DOI：
10.3109/13697137.2012.688078
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发表时间：
2013-04-01
期刊：
影响因子：
2.8
通讯作者：
Hunter, M. S.
中科院分区：
文献类型：
--
作者：
Ayers, B.;Hunter, M. S.
尽管有大量关于更年期的研究，但很少有明确的证据表明血管舒缩症状对健康相关生活质量（HrQoL）的影响。因此，本研究描述了更年期妇女潮热和盗汗的HrQoL，并检查了HrQoL的预测因子。方法对140名每周报告至少10次潮热/盗汗（血管舒缩症状）的妇女进行评估访谈（包括病史、过去和现在的身心健康状况和绝经状况），并进行社会人口统计学和求助信息、HrQoL和潮热评定量表的问卷调查。结果：与美国SF-36标准和英国绝经妇女的一般样本相比，有血管舒缩症状的妇女报告的HrQoL有所降低；53%的人报告了共病的身体疾病，66%的人目前有社会心理问题；77%的人因更年期症状去看过医生；28%的人曾经接受过激素治疗，3%的人目前正在接受激素治疗。总体而言，较差的HrQoL与有问题的潮热、当前的社会心理问题、（年轻）年龄、（较高）体重指数和一般健康状况不佳有关。结论：与年龄匹配的标准和绝经妇女的一般样本相比，有血管舒缩症状的相对健康的中年妇女报告的HrQoL降低。潮热的问题等级，而不是频率，与HrQoL降低有关，健康和社会心理因素也是如此。
Objectives Despite a large body of research on menopause, there is little definitive evidence of the impact of vasomotor symptoms on health-related quality of life (HrQoL). Therefore, this study describes the HrQoL of menopausal women with hot flushes and night sweats and examines predictors of HrQoL.Methods A total of 140 women reporting at least ten hot flushes/night sweats (vasomotor symptoms) a week for at least a month completed an assessment interview (including medical history, past and current physical and mental health and menopausal status) and questionnaires eliciting sociodemographic and help-seeking information, HrQoL and the Hot Flush Rating Scale.Results Women with vasomotor symptoms reported somewhat reduced HrQoL compared to SF-36 US norms and a general sample of UK menopausal women; 53% reported comorbid physical illness and 66% had current psychosocial concerns; 77% had visited their doctor about menopausal symptoms; 28% were past and 3% current users of hormone therapy. Overall, poor HrQoL was associated with having problematic hot flushes, current psychosocial concerns, (younger) age, (higher) body mass index and poor general health.Conclusions This sample of relatively healthy mid-aged women with vasomotor symptoms reported reduced HrQoL compared to age-matched norms and a general sample of menopausal women. Problem rating, rather than frequency, of hot flushes was associated with reduced HrQoL, as were health and psychosocial factors.