Soft-landing of peptide ions onto self-assembled monolayer surfaces: an overview

Soft-landing of peptide ions onto self-assembled monolayer surfaces: an overview
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DOI:
10.1039/b712710c
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发表时间:
2008-01-01
影响因子:
3.3
通讯作者:
Hadjar, Omar
Hadjar, Omar
中科院分区:
化学2区
文献类型:
--
作者:
Laskin, Julia;Wang, Peng;Hadjar, Omar

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本文综述了近年来肽离子在自组装单分子层表面软着陆和反应性着陆的研究进展。肽离子是特别有吸引力的模型系统,它提供了对软着陆蛋白质行为的重要见解,而自组装膜提供了一个方便灵活的平台,用于定制金属和半导体表面的界面特性。质量选择离子在表面上的沉积伴随着许多过程,包括电荷减少、中和、共价和非共价结合以及离子和分子从基底的热解吸。影响这些过程之间的竞争的因素进行了讨论。
This review is focused on what has been learned in recent research studies concerned with fundamental aspects of soft-landing and reactive landing of peptide ions on self-assembled monolayer surfaces (SAMs). Peptide ions are particularly attractive model systems that provide important insights on the behavior of soft landed proteins, while SAMs provide a convenient and flexible platform for tailoring the interfacial properties of metals and semiconductor surfaces. Deposition of mass-selected ions on surfaces is accompanied by a number of processes including charge reduction, neutralization, covalent and non-covalent binding, and thermal desorption of ions and molecules from the substrate. Factors that affect the competition between these processes are discussed.