Integrated Electromicrobial Conversion of CO2 to Higher Alcohols
Integrated Electromicrobial Conversion of CO2 to Higher Alcohols
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DOI：
10.1126/science.1217643
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发表时间：
2012-03-30
期刊：
影响因子：
56.9
通讯作者：
Liao, James C.
中科院分区：
文献类型：
--
作者：
Li, Han;Opgenorth, Paul H.;Liao, James C.
利用电能的主要挑战之一是其储存的效率。目前的方法，如化学电池、液压泵和水分离，存在能量密度低或与现有交通基础设施不兼容的问题。在这里，我们报道了一种将电能以化学能的形式储存在高级醇中的方法，这种高级醇可以用作液体运输燃料。我们利用基因工程技术，在以二氧化碳为唯一碳源、电力为唯一能量输入的电生物反应器中，对自养微生物Ralstonia eutrohaH16进行了基因工程，使其产生异丁醇和3-甲基-1-丁醇。该工艺集电化学生产甲酸盐、生物固定二氧化碳和高级醇合成于一体，为电力驱动的二氧化碳生物转化为商业化学品开辟了可能性。
One of the major challenges in using electrical energy is the efficiency in its storage. Current methods, such as chemical batteries, hydraulic pumping, and water splitting, suffer from low energy density or incompatibility with current transportation infrastructure. Here, we report a method to store electrical energy as chemical energy in higher alcohols, which can be used as liquid transportation fuels. We genetically engineered a lithoautotrophic microorganism,Ralstonia eutrophaH16, to produce isobutanol and 3-methyl-1-butanol in an electro-bioreactor using CO2as the sole carbon source and electricity as the sole energy input. The process integrates electrochemical formate production and biological CO2fixation and higher alcohol synthesis, opening the possibility of electricity-driven bioconversion of CO2to commercial chemicals.