Associations of key diet-quality indexes with mortality in the Multiethnic Cohort: the Dietary Patterns Methods Project
Associations of key diet-quality indexes with mortality in the Multiethnic Cohort: the Dietary Patterns Methods Project
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DOI：
10.3945/ajcn.114.090688
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发表时间：
2015-03-01
影响因子：
7.1
通讯作者：
Kolonel, Laurence N.
中科院分区：
文献类型：
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作者：
Harmon, Brook E.;Boushey, Carol J.;Kolonel, Laurence N.
背景：健康的饮食模式与健康和长寿密切相关。然而，在美国不同人群中关于饮食模式和死亡率的前瞻性研究是有限的。目的：我们评估了以下4项饮食质量指数[2010年健康饮食指数(HEI-2010)、替代HEI-2010(AHEI-2010)、地中海饮食替代评分(AMED)和阻止高血压的饮食方法(DASH)]预测各种原因、心血管疾病(CVD)和癌症死亡风险的能力。设计：来自多种族科霍特的白人、非裔美国人、夏威夷原住民、日裔美国人和拉美裔成年人(n=215,782)。计算每个饮食指数的分数，并将其划分为男性和女性的五分位数。在13-18年的随访期内记录死亡率。结果：在男性和女性中，高的HEI-2010、AHEI-2010、AMED和DASH评分均与全因死亡、心血管疾病和癌症的风险呈负相关(所有模型的P趋势均为0.0001)。对于男性，当比较最低和最高五分位数时，HEI-2010与各种原因的死亡率(HR：0.75；95%CI：0.71，0.79)、心血管疾病(HR：0.74；95%CI：0.69，0.81)和癌症(HR：0.76；95%CI：0.70，0.83)的降低一致相关。在女性中，AHEI和AMED显示全因死亡率大幅下降(HR：0.78；95%CI：0.74，0.82)，AHEI显示心血管疾病大幅下降(HR：0.76；95%CI：0.69，0.83)，AMED显示癌症大幅下降(HR：0.84；95%CI：0.76，0：92)。结论：在美国多民族人群中，这些结果表明，在成年男性和女性中，饮食质量指数得分高的饮食模式与各种原因、心血管疾病和癌症死亡的风险较低相关。
Background: Healthy dietary patterns have been linked positively with health and longevity. However, prospective studies in diverse populations in the United States addressing dietary patterns and mortality are limited.Objective: We assessed the ability of the following 4 diet-quality indexes [the Healthy Eating Index-2010 (HEI-2010), the Alternative HEI-2010 (AHEI-2010), the alternate Mediterranean diet score (aMED), and the Dietary Approaches to Stop Hypertension (DASH)] to predict the reduction in risk of mortality from all causes, cardiovascular disease (CVD), and cancer.Design: White, African American, Native Hawaiian, Japanese American, and Latino adults (n = 215,782) from the Multiethnic Cohort completed a quantitative food-frequency questionnaire. Scores for each dietary index were computed and divided into quintiles for men and women. Mortality was documented over 13-18 y of follow-up. HRs and 95% CIs were computed by using adjusted Cox models.Results: High HEI-2010, AHEI-2010, aMED, and DASH scores were all inversely associated with risk of mortality from all causes, CVD, and cancer in both men and women (P-trend < 0.0001 for all models). For men, the HEI-2010 was consistently associated with a reduction in risk of mortality for all causes (HR: 0.75; 95% CI: 0.71, 0.79), CVD (HR: 0.74; 95% CI: 0.69, 0.81), and cancer (HR: 0.76; 95% CI: 0.70, 0.83) when lowest and highest quintiles were compared. In women, the AHEI and aMED.showed large reductions for all-cause mortality (HR: 0.78; 95% CI: 0.74, 0.82), the AHEI showed large reductions for CVD (HR: 0.76; 95% CI: 0.69, 0.83), and the aMED showed large reductions for cancer (HR: 0.84; 95% CI: 0.76, 0: 92).Conclusion: These results, in a US multiethnic population, suggest that consuming a dietary pattern that achieves a high diet-quality index score is associated with lower risk of mortality from all causes, CVD, and cancer in adult men and women.