Alcohol-induced euphoria: Exclusion of serotonin
Alcohol-induced euphoria: Exclusion of serotonin
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DOI：
10.1093/alcalc/36.1.22
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发表时间：
2001-01-01
影响因子：
2.8
通讯作者：
Badawy, AAB
中科院分区：
文献类型：
--
作者：
Morgan, CJ;Badawy, AAB
在前30分钟急性酒精消费后，三个禁食正常男性志愿者，没有增加循环色氨酸的可用性发生在大脑。相反，观察到小幅下降，随后变得更强。我们的结论是，从这个初步的研究，大脑5-羟色胺水平不增加酒精摄入后，由正常受试者，因此，吲哚胺是不太可能介导的酒精的欣快效应。
During the first 30 min after acute ethanol consumption by three fasting normal male volunteers, no increase in circulating tryptophan availability to the brain occurred. On the contrary, a small decrease was observed, which became stronger subsequently. We conclude from this preliminary study that brain serotonin levels are not increased after alcohol intake by normal subjects and that, consequently, this indolylamine is unlikely to mediate the euphoric effects of alcohol.