Measurement of cerebral circulation time by contrast-enhanced Doppler sonography
Measurement of cerebral circulation time by contrast-enhanced Doppler sonography
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DOI：
10.1159/000016043
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发表时间：
2000-03-01
影响因子：
2.9
通讯作者：
Valdueza, M
中科院分区：
文献类型：
--
作者：
Hoffmann, O;Weih, M;Valdueza, M
We present a new, non-invasive ultrasound method for the measurement of cerebral circulation time. After injection of a galactose-based echo-contrast agent (Levovist) into an antecubital vein, cerebral circulation time is measured as the interval between the beginning of a stable signal enhancement of at least 5 dB in the internal carotid artery and in the ipsilateral internal jugular vein. Both vessels are insonated simultaneously at the mandibular angle using a single 2-MHz range-gated transducer. For this study, 25 healthy volunteers ranging in age from 23 to 55 years (30.1 +/- 7.5 years; mean +/- SD) were examined. Cerebral circulation time was 5.6 +/- 1.7 s without significant side-to-side or sex-related differences. Measurement of circulation times offers a new possibility for the employment of echo-contrast agents in functional ultrasound. Copyright (C) 2000 S. Karger AG, Basel.
