Relationship between lamina cribrosa curvature and the microvasculature in treatment-naive eyes
Relationship between lamina cribrosa curvature and the microvasculature in treatment-naive eyes
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DOI：
10.1136/bjophthalmol-2019-313996
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发表时间：
2020-03-01
影响因子：
4.1
通讯作者：
Mari, Jean Martial
中科院分区：
文献类型：
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作者：
Kim, Ji-Ah;Kim, Tae-Woo;Mari, Jean Martial
目的探讨正常眼压性青光眼（normal-tensionglaucoma，NTG）患者和健康人筛板（laminarcribrosa，LC）曲率和微血管之间的关系。使用光谱域光学相干断层扫描（OCT）扫描视神经乳头（ONH）区域，以检查LC曲率，量化为LC曲率指数（LCCI）。对ONH区域进行OCT血管造影，以确定从LC水平分割的层获得的正面图像中的LC血管密度（LCVD）。结果LCCI大于对照组（9.53 ± 1.33 vs 6.55 ± 1.02，p
Background/Aims To investigate the relationship between the lamina cribrosa (LC) curvature and the microvasculature within the LC in treatment-naive eyes with normal-tension glaucoma (NTG) and in healthy eyes.Methods Forty-one eyes with treatment-naive NTG and 41 age and sex-matched healthy control eyes were included. The optic nerve head (ONH) area was scanned using spectral-domain optical coherence tomography (OCT) to examine the LC curvature quantified as the LC curvature index (LCCI). OCT angiography of the ONH area was performed to determine the LC vessel density (LCVD) in the en face images obtained from the layer segmented at the level of the LC. The LCVD was calculated as the percentage area occupied by vessels within the measured region.Results The LCCI was larger (9.53 +/- 1.33 vs 6.55 +/- 1.02, p