Moderators and mediators of a Web-based computer-tailored smoking cessation program among nicotine patch users
Moderators and mediators of a Web-based computer-tailored smoking cessation program among nicotine patch users
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DOI：
10.1080/14622200601039444
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发表时间：
2006-12-01
影响因子：
4.7
通讯作者：
West, Robert
中科院分区：
文献类型：
--
作者：
Strecher, Victor J.;Shiffman, Saul;West, Robert
本研究的目的是探讨基于万维网的定制行为戒烟材料的功效的调节和中介因素。设计是在英格兰和爱尔兰共和国进行的两组随机对照试验。参与者是3971名购买了特定品牌尼古丁贴片并登录使用免费网络行为支持程序的受试者。干预是基于网络的定制行为戒烟材料或基于网络的非定制材料。在12周随访时通过基于互联网的调查评估了10周持续戒烟率。潜在的治疗调节剂进行了检查，使用亚组的既定或可能的戒烟预测。治疗中介检查包括6周的后续措施的程序相关性和基于网络的材料阅读量。在检查的所有亚组中，基于网络的定制干预的受试者更有可能在12周随访时报告10周的连续禁欲。重要的调节因素，表明一个显着的差异，在计划的效力之间的亚组，包括存在烟草相关的疾病（患有烟草相关疾病的受试者之间的治疗-对照差异较大），家中有不吸烟的儿童（家庭中有不吸烟儿童的受试者之间的治疗-对照差异较大），和频繁饮酒（饮酒量较高的受试者之间的治疗-对照差异较大）。在6周随访时感知的计划相关性是在12周随访时停止的中介因素。定制程序的稳健结果可以通过在治疗条件中使用的定制策略来解释。调节变量对于在定制的消息传递中解决可能特别有用。感知信息相关性的中介因素可以提供有效的程序剪裁的部分机制。
The aim of this study was to examine moderating and mediating factors of the efficacy of World Wide Web-based tailored behavioral smoking cessation materials. The design was a two-group randomized controlled trial in England and the Republic of Ireland. Participants were 3971 subjects who purchased a particular brand of nicotine patch and logged on to use a free Web-based behavioral support program. The intervention was Web-based tailored behavioral smoking cessation materials or Web-based nontailored materials. The 10-week continuous abstinence rate was assessed by Internet-based survey at 12-week follow-up. Potential treatment moderators were examined using subgroups of established or possible predictors of smoking cessation. Treatment mediators examined included 6-week follow-up measures of program relevance and amount of the Web-based materials read. Within all subgroups examined, subjects in the Web-based tailored intervention were more likely to report 10-week continuous abstinence at 12-week follow-up. Significant moderators, indicating a significant difference in program efficacy between subgroups, included presence of a tobacco-related illness (larger treatment-control differences among subjects with a tobacco-related illness), presence of nonsmoking children in the household (larger treatment-control differences among subjects with nonsmoking children in the household), and frequent alcohol consumption (larger treatment-control differences among subjects with higher alcohol consumption). Perceived program relevance at 6-week follow-up was a mediator of cessation at 12-week follow-up. Robust results of the tailored program may be explained by the tailoring strategies utilized in the treatment conditions. Moderating variables may be particularly useful to address in tailored messaging. The mediating factor of perceived message relevance may provide a partial mechanism of effective program tailoring.