Evidence that the coproporphyrinogen oxidase activity of rat liver is situated in the intermembrane space of mitochondria.
Evidence that the coproporphyrinogen oxidase activity of rat liver is situated in the intermembrane space of mitochondria.
复制标题
有证据表明大鼠肝脏的粪卟啉原氧化酶活性位于线粒体的膜间隙中。
作者：
G. Elder;Heath Park
大鼠肝脏线粒体外膜优先破裂释放粪卟啉原氧化酶，并与膜间隙成分平行。粪卟啉原III通过自由渗透的外膜进入细胞膜。在血红素合成完成之前，原卟啉原IX或原卟啉IX必须穿过内膜。
Preferential rupture of the outer membrane of mitochondria from rat liver releases coproporphyrinogen oxidase in parallel with components of the intermembrane space. Coproporphyrinogen III enters the mitochondrion through the freely-permeable outer membrane. Either protoporphyrinogen IX or protoporphyrin IX must then cross the inner membrane before haem synthesis can be completed.