Semi-chronic motorized microdrive and control algorithm for autonomously isolating and maintaining optimal extracellular action potentials
Semi-chronic motorized microdrive and control algorithm for autonomously isolating and maintaining optimal extracellular action potentials
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DOI：
10.1152/jn.00369.2004
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发表时间：
2005-01-01
影响因子：
2.5
通讯作者：
Burdick, JW
中科院分区：
文献类型：
--
作者：
Cham, JG;Branchaud, EA;Burdick, JW
开发了一种系统，可以自主定位记录电极，以隔离和保持最佳质量的细胞外信号。该系统由一个新颖的电动微型记录微驱动器和控制算法。该微驱动器是专为慢性操作，可以独立定位四个玻璃涂层铂铱电极的微米精度超过5毫米的范围内使用小型（3毫米直径）压电线性致动器。自主定位算法旨在检测、对齐和聚类动作电位，然后命令微驱动器优化和维持神经信号。该系统被证明是能够在猴子皮层组织的自主操作。
A system was developed that can autonomously position recording electrodes to isolate and maintain optimal quality extracellular signals. The system consists of a novel motorized miniature recording microdrive and a control algorithm. The microdrive was designed for chronic operation and can independently position four glass-coated Pt-Ir electrodes with micrometer precision over a 5-mm range using small (3 mm diam) piezoelectric linear actuators. The autonomous positioning algorithm is designed to detect, align, and cluster action potentials and then command the microdrive to optimize and maintain the neural signal. This system is shown to be capable of autonomous operation in monkey cortical tissue.