Copper-Catalyzed Electrophilic Amination of Alkoxyarylsilanes
Copper-Catalyzed Electrophilic Amination of Alkoxyarylsilanes
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铜催化烷氧基芳基硅烷的亲电胺化
DOI：
10.1002/ejoc.202000562
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发表时间：
2020
影响因子：
2.8
通讯作者：
Yorimitsu Hideki
中科院分区：
文献类型：
--
作者：
Zhang Qian;Hitoshio Kenshiro;Saito Hayate;Shimokawa Jun;Yorimitsu Hideki
本文报道了铜催化的简单烷氧基芳基硅烷与N-苯甲酰氧基胺的胺化反应。银氟化物作为化学计量的碱以及允许催化过程进行的必不可少的活化剂。在温和的反应条件下，将多烷氧基芳基硅烷如三烷氧基芳基硅烷和二烷氧基芳基硅烷转化为相应的叔苯胺。
We report a copper‐catalyzed amination reaction between simple alkoxyarylsilanes andN‐benzoyloxyamines. Silver fluoride serves as a stoichiometric base as well as an indispensable activator that allows the catalytic process to proceed. Multiply alkoxylated arylsilanes, such as trialkoxyarylsilanes and dialkoxyarylsilanes were transformed into the corresponding tertiary anilines under mild reaction conditions.