An item-level response shift study on the change of health state with the rating of asthma-specific quality of life: a report from the PROMIS(®) Pediatric Asthma Study.

An item-level response shift study on the change of health state with the rating of asthma-specific quality of life: a report from the PROMIS(®) Pediatric Asthma Study.
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DOI:
10.1007/s11136-016-1290-x
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发表时间:
2016-06
期刊:
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
影响因子:
--
通讯作者:
Huang IC
Huang IC
中科院分区:
其他
文献类型:
--
作者:
Gandhi PK;Schwartz CE;Reeve BB;DeWalt DA;Gross HE;Huang IC

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检查与哮喘相关健康状态变化相关的项目级反应变化(即哮喘控制状态的变化和呼吸问题的全球变化评级(GRC))。研究样本包括238名8岁至17.9岁的哮喘儿童,他们完成了基线时的儿童哮喘生活质量问卷(PAQLQ)的症状、情绪功能和活动限制领域,并进行了随访评估。结构方程模型被用来评估与哮喘相关健康状态变化相关的条目水平反应变化,并调整混杂变量的影响。使用Cohen的效应大小估计项目水平反应漂移的大小及其对领域分数变化的影响。我们没有发现项目级别的反应转移的实例。然而,由于呼吸问题,有两项测量偏差与GRC有关。具体地说,与那些因呼吸问题而GRC恶化的儿童相比,由于呼吸问题而GRC较好/接近相同的哮喘儿童在随访时在情绪领域的一个项目上的得分较低。此外,与因呼吸问题而GRC恶化的儿童相比,由于呼吸问题而GRC较好/接近相同的哮喘儿童在基线时在症状领域的另一项得分更高。测量偏差的影响很小,并且不会对领域分数随时间的变化产生偏差。哮喘儿童没有出现项目水平的反应变化,但出现了两个测量偏差的例子。然而,这些衡量问题的影响可以忽略不计。
To examine item-level response shift associated with the change in asthma-related health state (i.e., change in asthma control status and global rating of change (GRC) in breathing problems). Study sample comprised 238 asthmatic children who were between 8 and 17.9 years and completed the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) symptoms, emotion function, and activity limitation domains at baseline and a follow-up assessment. Structural equation modeling was implemented to assess item-level response shift associated with the change in asthma-related health state with the adjustment for the influence of confounding variables. The magnitude of item-level response shift and its influence on the change of domain scores was estimated using Cohen’s effect sizes. We found no instances of item-level response shift. However, two items were identified with measurement bias related to GRC due to breathing problems. Specifically, asthmatic children with better/about the same GRC due to breathing problems reported lower scores for one item in the emotional domain at follow-up compared to those with deteriorated GRC due to breathing problems. In addition, asthmatic children with better/about the same GRC due to breathing problems reported better scores for another item in the symptom domain at baseline compared to those with deteriorated GRC due to breathing problems. The impact of measurement bias was small and did not bias the change of domain scores over time. No item-level response shift, but two instances of measurement bias, appears in asthmatic children. However, the impact of these measurement issues is negligible.