Quantitative ultrasound and bone mineral density are equally strongly associated with risk factors for osteoporosis
Quantitative ultrasound and bone mineral density are equally strongly associated with risk factors for osteoporosis
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DOI：
10.1359/jbmr.2001.16.2.406
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发表时间：
2001-02-01
影响因子：
6.2
通讯作者：
Fogelman, I
中科院分区：
文献类型：
--
作者：
Frost, ML;Blake, GM;Fogelman, I
由于资源不允许所有妇女进行骨质疏松症筛查，临床风险因素通常用于确定那些骨折风险增加的个体，然后通过骨密度测定进行评估。本研究的目的是比较跟骨定量超声（QUS）和轴向骨矿物质密度（BMD）的T和Z评分在一个大组的妇女，一些没有临床危险因素和其他一个或多个骨质疏松症的危险因素。研究人群包括1115名绝经前和绝经后妇女。一个530名妇女的亚组被用来构建参考数据计算T和Z分数。共有786名妇女被发现有以下一个或多个风险因素：（i）25岁以上非创伤性骨折，（ii）X线骨量减少报告，（iii）易患疾病或使用已知影响骨代谢的治疗，（iv）25岁以前过早绝经或闭经超过6个月，（v）骨质疏松症的家族史，（vi）身体。质量指数CBR（BMI）
Because resources do not allow all women to be screened for osteoporosis, clinical risk factors are often used to identify those individuals at increased risk of fracture who are then assessed by bone densitometry. The aim of this study was to compare calcaneal quantitative ultrasound (QUS) and axial bone mineral density (BMD) T and Z scores in a large group of women, some with no clinical risk factors and others with one or more risk factors for osteoporosis. The study population consisted of 1115 pre- and postmenopausal women. A subgroup of 530 women was used to construct reference data for calculating T and Z scores. A total of 786 women was found to have one or more of the following risk factors: (i) atraumatic fracture since the age of 25 years, (ii) report of X-ray osteopenia, (iii) predisposing medical condition or use of therapy known to affect bone metabolism, (iv) premature menopause before the age of 25 years or a history of amenorrhea of longer than 6 months duration, (v) family history of osteoporosis, (vi) body. mass index CBR (BMI)