NUREBASE:: database of nuclear hormone receptors
NUREBASE:: database of nuclear hormone receptors
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DOI：
10.1093/nar/30.1.364
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发表时间：
2002-01-01
影响因子：
14.9
通讯作者：
Robinson-Rechavi, M
中科院分区：
文献类型：
--
作者：
Duarte, J;Perrière, G;Robinson-Rechavi, M
核激素受体是一类丰富的配体激活的转录调节因子，在所有动物中都有不同数量的发现。基于我们管理核受体官方命名的经验，我们开发了NUREBASE，一个包含蛋白质和DNA序列的数据库，回顾了所有核受体的蛋白质排列和系统发育，分类和注释。审查后的NUREBASE由NUREBASE_DAILY完成，每24小时自动更新一次。两个数据库都是在客户端/服务器架构下组织的，客户端使用Java编写，可以在任何平台上运行。这个名为FamFetch的客户端集成了一个图形界面，允许选择家族，并操纵系统发育和排列。NUREBASE序列数据也可以通过万维网服务器访问，允许复杂的查询。有关访问和安装NUREBASE的所有信息可在http://www.ens-lyon.fr/LBMC/laudet/nurebase.html上找到。
Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and annotations for all nuclear receptors. The reviewed NUREBASE is completed by NUREBASE_DAILY, automatically updated every 24 h. Both databases are organized under a client/server architecture, with a client written in Java which runs on any platform. This client, named FamFetch, integrates a graphical interface allowing selection of families, and manipulation of phylogenies and alignments. NUREBASE sequence data is also accessible through a World Wide Web server, allowing complex queries. All information on accessing and installing NUREBASE may be found at http://www.ens-lyon.fr/LBMC/laudet/nurebase.html.