Saponins from the flower buds of Buddleja officinalis

Saponins from the flower buds of Buddleja officinalis
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DOI:
10.1021/np0300131
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发表时间:
2004-01-01
影响因子:
5.1
通讯作者:
Nikaido, T
Nikaido, T
中科院分区:
生物学2区
文献类型:
--
作者:
Guo, HZ;Koike, K;Nikaido, T

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从牛头草(budleja officinalis)花蕾中分离到了5个新皂苷,分别为牛头草苷A、毛蕊花苷、苯乙基2-葡萄糖苷、紫锥花苷和苯乙基醇8- o - β - d -葡萄糖苷(1- bbb2)- β - d -葡萄糖苷。利用光谱学和化学方法鉴定了1 ~ 5个化合物的结构,并评价了这些化合物对HL-60白血病细胞的抑制作用。
Five new saponins, mimengosides C-G (1-5), were isolated from the flower buds of Buddleja officinalis along with five known compounds, namely, songaroside A, acteoside, phenylethyl 2-glucoside, echinacoside, and phenylethyl alcohol 8-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside. The structures of 1-5 were elucidated using spectroscopic and chemical methods, and these compounds were evaluated for their inhibitory effects against HL-60 leukemia cells.