Functional information in SWISS-PROT: the basis for large-scale characterisation of protein sequences.
Functional information in SWISS-PROT: the basis for large-scale characterisation of protein sequences.
复制标题
DOI：
10.1093/bib/2.1.9
复制
发表时间：
2001-03-01
影响因子：
9.5
通讯作者：
Apweiler, R
中科院分区：
文献类型：
--
作者：
Apweiler, R
随着序列数据库的快速发展，人们越来越需要对新预测的蛋白质进行可靠的功能表征和注释。为了科普如此大的数据量，需要更快和更有效的蛋白质序列表征和注释手段。一个有前途的方法是自动大规模的功能表征和注释，这是有限的人类互动产生的。然而，这种方法严重依赖可靠的数据来源。SWISS-PROT蛋白质序列数据库由于其高水平的功能信息在这里发挥着至关重要的作用。
With the rapid growth of sequence databases, there is an increasing need for reliable functional characterisation and annotation of newly predicted proteins. To cope with such large data volumes, faster and more effective means of protein sequence characterisation and annotation are required. One promising approach is automatic large-scale functional characterisation and annotation, which is generated with limited human interaction. However, such an approach is heavily dependent on reliable data sources. The SWISS-PROT protein sequence database plays an essential role here owing to its high level of functional information.