[Professor Ling Changquan's experience in treating primary liver cancer: an analysis of herbal medication].
[Professor Ling Changquan's experience in treating primary liver cancer: an analysis of herbal medication].
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DOI：
10.3736/jcim20081203
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发表时间：
2008-12-01
期刊：
影响因子：
--
通讯作者：
Yue, Xiao-qiang
中科院分区：
文献类型：
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作者：
Sun, Zhen;Su, Yong-hua;Yue, Xiao-qiang
收集长海医院门诊部凌长泉教授就诊的552例(2020张有效处方)原发性肝癌患者的临床资料。用频数法总结方剂用药的性质、风味和经络分布，用Logistic回归分析辨证用药的特点。采用聚类分析方法对所用配伍中草药进行了聚类分析。所有的数据都结合专家的经验进行了分析。结果表明，常用中药多为健脾开胃、解毒抑瘤、活血化瘀药。这些草本植物大多性质平淡或凉爽，主要有甜、苦或苦的味道。研究还发现，治疗气虚最常用的草药有黄芪、白术、太子参；血虚用药有白术、大枣；阴虚用药有山茱萸、麦冬；治湿用药有黄连、车前子、茯苓；治热用药有茉莉花、柴胡；治疗气滞的有桃子、赤芍；郁金、木通、柴胡。通过聚类分析，共归纳出19对中草药。
On the basis of outpatients' medical records concerning primary liver cancer (PLC), data of 552 patients (with 2020 effective prescriptions) from the Outpatient Department of Changhai Hospital treated by Professor Ling Changquan were collected. The nature, flavor and meridian distribution of the herbs used in the prescriptions were summarized by frequency method, and the features of the herbs used according to syndrome differentiation were analyzed by logistic regression. The couple herbs used were analyzed by cluster analysis. All the data were analyzed in combination with the experience of the specialist. It showed that most of the frequently used herbs were herbs for invigorating the spleen to promote appetite, removing toxic materials to inhibit tumor growth, and activating blood circulation to dissipate blood stasis. These herbs are mostly of plain or cool nature, and mainly of sweet, bitter, or acrid taste. It also showed that the most frequently used herbs for qi deficiency were Astragalus membranaceus, Atractylodes macrocephala, and Pseudostellariae; Caulis Spatholobi and Chinese jujube for blood asthenia; Fructus Corni and Ophiopogon japonicus for yin deficiency; Agastache rugosa, Semen Plantaginis and Poria for water-dampness; cape jasmine fruit and baikal skullcap root for heat excess; peach seed and Radix Paeoniae Rubra for blood stasis; Curcuma wenyujin, Akebia trifoliata and Bupleurum chinese for qi stagnation. A total of 19 pairs of couple herbs were summarized by the cluster analysis.